tag:blogger.com,1999:blog-19102494.post3501580593641581163..comments2023-10-07T07:52:24.587-07:00Comments on CLL Diary: The chemo monster mash: FCR vs. FCADavid Arensonhttp://www.blogger.com/profile/13876562687586184006noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-19102494.post-68157476199195298272010-11-28T19:37:53.502-07:002010-11-28T19:37:53.502-07:00In 2007, I was training for an attempt at qualifyi...In 2007, I was training for an attempt at qualifying for the Boston Marathon (last ran in 2004).<br />Ran a tune up marathon and indications were that I was ready. Four weeks later I couldn't run three miles without stopping to walk and was diagnosed with CLL (unmutated IgVH, positive ZAP 70 and CD 38). Was told I wouldn't have the stamina for marathons anymore. Spent a year doing 2/day workouts to trying and train my body to run through the fatigue. Ran a marathon Feb 2009, although 1 hr slower than usual times. In the last 23 months, I have now run 26 marathons. At first the increase in counts was slow (doubled in 1.5 years). Now it has doubled in a 3 month period and chemo has been recommended. I have been unable to find any good information for my question: Will it be detrimental to continue to run marathons during chemo. I understand the necessity of wearing a mask during travel and contact with people, but what else? I am now 63.Phillipnoreply@blogger.comtag:blogger.com,1999:blog-19102494.post-19744707623014478112010-08-18T16:55:53.666-07:002010-08-18T16:55:53.666-07:00I am a 29 year old mother of 3 young children. I w...I am a 29 year old mother of 3 young children. I was diagnosed with SLL in April of this year but just had a visit at Duke University a few weeks ago and they are saying they believe I have CLL & are recommending FCR for my next round of Chemo.<br /><br />Thank You for your incite into this medicine. I have been trying to learn more about it so I can make an informed decision in a few weeks on which route I am going to be taking in my journey. <br /><br />I recently started blogging about my medial adventures. http://tarasmedicaladventrues.blogspot.com/?zx=8145de1826732d34Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19102494.post-81463514581868186262009-08-19T14:35:08.617-07:002009-08-19T14:35:08.617-07:00Upon first diagnosis, thirteen years ago, I had si...Upon first diagnosis, thirteen years ago, I had six months of fludarabine, and it put me into remission, which lasted between a year and two. (I'm not sure exactly how long - I didn't go back to the doc for three years, until I knew I was sick again.) The doc started me on fludara again, and I had two cycles of it. Then the doc retired and reommended a new, younger doc. The new guy said I should not have been given the two cycles of fludara, because it can cause a fatal anemia. I then had six months of rituxan, which put me into a remission I'm still enjoying. Who knows, maybe the secret is two cycles of fludara, followed by the rituxan!? It's all big roulette wheel.<br /><br />DennyAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-19102494.post-14793756905526737652009-08-16T21:04:28.758-07:002009-08-16T21:04:28.758-07:00Anything that includes fludarabine is problematic ...Anything that includes fludarabine is problematic in terms of the long-lasting and profound immunosuppression that accompanies the use of the drug. Ideally, one would avoid fludarabine either singly or in combination if at all possible. <br /><br />There are many options that don't include the drug. And even if it appears to be inevitable that fludarabine be used, one might consider seriously the use of FCR-lite.Anonymousnoreply@blogger.com