tag:blogger.com,1999:blog-19102494.post3693128439521521775..comments2023-10-07T07:52:24.587-07:00Comments on CLL Diary: A real pain in the neckDavid Arensonhttp://www.blogger.com/profile/13876562687586184006noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-19102494.post-60773577392609899722011-12-22T10:57:56.531-07:002011-12-22T10:57:56.531-07:00Hang on Sloopy,
I am sorry to hear about the lates...Hang on Sloopy,<br />I am sorry to hear about the latest episode of Flare/infection. Wishing you a speedy recovery.<br /><br />I see that you have been on rituximab before...<br /><br />I was at ASH this year and an interesting piece of information related to Lymphoma...but would be interesting to see if it ever translates over to CLL. <br /><br />lenalidomide given after rituximab seemed to relieve rituximab resistance. Dexamethasone improved tolerability with regards to tumor flare and other side effects.<br /><br />http://ash.confex.com/ash/2011/webprogram/Paper45076.html<br /><br />Keep fighting the good fight.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19102494.post-57279315466912106532011-12-09T10:44:00.395-07:002011-12-09T10:44:00.395-07:00Stew,
Revlimid is an immunomodulator. It gooses t...Stew,<br /><br />Revlimid is an immunomodulator. It gooses the NK and T cells to attack the CLL cells. These killer cells rush to the site of the CLL (lymph nodes) and thus the swelling. (There are no doubt other contributors to the swelling, but that's the gist of it.) Tumor flare usually goes down after two to three weeks. In my case, for some reason, even though I have taken Revlimid on and off since March 2010, the recent tumor flare was much worse than it ever had been. There was every sign that had I continued taking it, it would have caused even more swelling, which was already reaching untenable levels.<br /><br />DavidDavid Arensonhttps://www.blogger.com/profile/13876562687586184006noreply@blogger.comtag:blogger.com,1999:blog-19102494.post-85807335028579456122011-12-08T04:24:34.698-07:002011-12-08T04:24:34.698-07:00HI dave ,
That looks really painful ,hope things h...HI dave ,<br />That looks really painful ,hope things have improved followed your blog from the start fantastic and so informative ,still slightly confused by the tumour flare why does it happen ?????<br /><br />Follow cll Student Nurse<br /><br />stew (england)Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19102494.post-78253135503728621942011-12-07T16:58:07.035-07:002011-12-07T16:58:07.035-07:00David, We are glad to see you post again but so so...David, We are glad to see you post again but so sorry to hear of this latest experience. It looks painful and sounds frightening. You and I have similar cases which were diagnosed about the same time, so my husband and I really appreciate your blog. And I too am now a Revlimid buddy - I've been on the dose escalation trial since March 2011, up to 25 mg daily for the last 5 or more months - depending on my starting dose, which is blind to Dr Kipps and I.<br />I will continue to send you my best wishes and hope that someday I can do something for you.<br />Cynthia<br />Diagnosed 3/2003 at Age 47, unmutated, Zap 70 and CD 38+, <br />normal Fish. FCR 2004, Campath 2009, 2011 RevlimidCynthiahttps://www.blogger.com/profile/16177353732255845032noreply@blogger.comtag:blogger.com,1999:blog-19102494.post-23583915329950287632011-12-05T07:53:31.729-07:002011-12-05T07:53:31.729-07:00David... just a caveat...clindamycin is one of the...David... just a caveat...clindamycin is one of the more notorious antibiotics underling subsequent C diff. enterocolitis. As you were hospitalized for 3 days, your risk is further elevated. Most likely you'll be fine, but I would suggest that you ingest probiotics regularly and do not ignore abdominal pain, fever or diarrhea which could manifest even several weeks after completing the antibiotics.<br /><br /><br />Email or call me if you have any questions about this.<br /><br />Get well!!<br /><br />RickAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-19102494.post-78218832787942139422011-12-04T16:36:09.394-07:002011-12-04T16:36:09.394-07:00Your description on the phone was not even close t...Your description on the phone was not even close to the pictures. If you where a squirrel, you would have the whole winter supplies already collected. Take care and I will call you with my results.<br /><br /><br />Dave (your revlimid buddy)Anonymousnoreply@blogger.com