tag:blogger.com,1999:blog-19102494.post6048720092112438029..comments2023-10-07T07:52:24.587-07:00Comments on CLL Diary: Holy bendamustine, Batman! (B-R round two)David Arensonhttp://www.blogger.com/profile/13876562687586184006noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-19102494.post-6560747433053244662013-09-26T02:41:27.959-07:002013-09-26T02:41:27.959-07:00Sorry just read ur profile u r a professional writ...Sorry just read ur profile u r a professional writerharimohanhttps://www.blogger.com/profile/18105229701118099822noreply@blogger.comtag:blogger.com,1999:blog-19102494.post-42616391668956380882013-09-26T02:40:13.010-07:002013-09-26T02:40:13.010-07:00Dear David
You will sail through your regime and ...Dear David <br />You will sail through your regime and do well because I can sense a writer in you who observes and recounts on himself in lovely words <br />hariwrite.blogspot.comharimohanhttps://www.blogger.com/profile/18105229701118099822noreply@blogger.comtag:blogger.com,1999:blog-19102494.post-30555079986082304352012-08-30T13:56:16.333-07:002012-08-30T13:56:16.333-07:00Hi David,
Thanks for the updates, and I'm gla...Hi David,<br /><br />Thanks for the updates, and I'm glad to hear you were able to make it through all the infusion related complications.<br /><br />It's interesting what you had to say regarding Revlimid. My husband is taking this as a part of a clinical trial. He has psoriasis and arthritis, and the drug has cause both conditions to flare. The med was stopped temporarily and the improvement in psoriasis was immediate. It has brought his counts very close to the normal range. <br />We also feel the medication has amplified his already overactive immune system. Given the choice between continuing the med and potential other alternatives, the psoriasis/arthritis seems the lesser of two evils.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19102494.post-2118903761719719892012-08-30T13:32:29.034-07:002012-08-30T13:32:29.034-07:00Brian,
Thanks for your thoughts on this.
I real...Brian,<br /><br />Thanks for your thoughts on this. <br /><br />I realize I could benefit from the sort of detailed cytogenetic testing done by Dr. Byrd and other major researchers, which is out of my reach at the moment. So I am left with idle and somewhat uninformed speculation. <br /><br />My CD20 has not been tested in some time. Since I first had Rituxan in 2004, it gradually declined to a low level, but I suppose the situation could have reversed itself in the last couple of years. <br /><br />High tumor burden could have something to do with it, but I have had R with high tumor burden before without this reaction. Given that the Rituxan was resumed directly after the bendamustine ended, it's hard to imagine that the B had adequate time to reduce the tumor burden to any significant degree. I'll ask my oncologist about all this when I see him nest.<br /><br />Yes, we're all in this together. Glad to see from your blog -- which I recommend to all my readers -- that you're doing well.<br /><br />DavidDavid Arensonhttps://www.blogger.com/profile/13876562687586184006noreply@blogger.comtag:blogger.com,1999:blog-19102494.post-85684001105230768662012-08-30T04:33:03.082-07:002012-08-30T04:33:03.082-07:00David,
Cytogenetic studies would give a clearer pi...David,<br />Cytogenetic studies would give a clearer picture of your clonal evolution, but I doubt it would have any clinical impact.<br />A high tumor load with lots of CD20 for the Rituximab to grab may induce more infusion reactions. That's why the B 1st makes sense.<br />Stay strong. We are all in this together.<br />Brian<br />bkoffman.blogspot.comBrian Koffmanhttps://www.blogger.com/profile/13250684684103918493noreply@blogger.com